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Thesis

Inferring the translation speed and determining its relationship to the protein structure produced

Abstract:

The central dogma outlines the flow of information within a cell, whereby a DNA sequence is transcribed into RNA, which, in turn, is translated into a protein. This flow is unidirectional, meaning that once constructed, a protein should retain no knowledge of either the RNA or DNA sequence which led to its creation. Due to the degeneracy of the genetic code, multiple synonymous mRNA sequences can result in the same protein being produced. However, an increasing volume of experimental work ...

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Division:
MPLS
Department:
Statistics
Role:
Author

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Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:0ec0ed4d-2cb0-4587-9158-9d65276eb66c
Deposit date:
2017-05-14

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