RNA and glia at the Drosophila neuromuscular junction: importance for synaptic plasticity

Thesis

Glial cells are essential components of both human and invertebrate nervous systems, including in the fruit fly, Drosophila melanogaster. Historically, research has focused more on neurons, with glia and their role in synaptic plasticity being somewhat overlooked. It is generally accepted that synaptic plasticity requires messenger ribonucleic acid (mRNA) and proteins localising at synapses, but the role of glia and mRNA localisation within glia in this process has been comparatively overl...

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Authors: Gala, DS

• DOI: 10.5287/ora-dqnve7wy5
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: neuroscience; Drosophila; RNA; synaptic plasticity; glial cells; neurobiology; mRNA; glia
• Subjects: Molecular neuroscience; Drosophila melanogaster; RNA; Neurosciences; Myoneural junction; Messenger RNA; Neuroplasticity; Neuroglia