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Human metabolic profiles are stably controlled by genetic and environmental variation

Abstract:

1 H Nuclear Magnetic Resonance spectroscopy (1 H NMR) is increasingly used to measure metabolite concentrations in sets of biological samples for top-down systems biology and molecular epidemiology. For such purposes, knowledge of the sources of human variation in metabolite concentrations is valuable, but currently sparse. We conducted and analysed a study to create such a resource. In our unique design, identical and non-identical twin pairs donated plasma and urine samples longitudinally. ...

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Publisher copy:
10.1038/msb.2011.57

Authors


Nicholson, G More by this author
Rantalainen, M More by this author
Malmodin, D More by this author
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Journal:
Molecular Systems Biology
Volume:
7
Publication date:
2011
DOI:
EISSN:
1744-4292
URN:
uuid:0d1a7cb9-4275-45ac-b6f7-76acf84671ab
Source identifiers:
179695
Local pid:
pubs:179695

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