Characterisation of endometrial B cells and lymphocytes in the peri-implantation window

Thesis

Immunological regulation at the implantation site is a complex process, dysfunction may contribute to infertility, recurrent implantation failure (RIF) or recurrent pregnancy loss (RPL). Apart from endometrial NK and T cells, whose phenotypic profile and functional involvement have been recognised, evidence suggests that endometrial B cells may also have a potential role in reproductive pathologies. This thesis aimed to investigate endometrial immune profiles during human implantation, wit...

Expand abstract

Authors: Shen, M

• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: flow cytometry; recurrent implantation failure; recurrent pregnancy loss; T follicular helper cells; RNA-seq; B cells; endometrium
• Subjects: Reproductive health