Thesis
Identifying genetic determinants of impaired PfEMP1 export in Plasmodium falciparum-infected erythrocytes
- Abstract:
-
The virulence of Plasmodium falciparum is largely attributed to the ability of asexual blood-stage parasites to cytoadhere to the microvascular endothelium of the human host. This pathogenic behavior is mediated by the primary parasite virulence factor P. falciparum erythrocyte membrane protein 1 (PfEMP1), an understanding of which is crucial to develop interventions to ameliorate the morbidity and mortality of P. falciparum malaria. The work presented in this thesis describes the ap...
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Authors
Contributors
+ Newbold, C
Division:
MSD
Department:
NDM
Role:
Supervisor
+ Fairhurst, R
Division:
MSD
Department:
NDM
Role:
Supervisor
Funding
Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:0cc3f09c-9178-448b-92f8-8f9564398585
- Local pid:
- ora:10959
- Deposit date:
- 2015-04-13
Terms of use
- Copyright holder:
- Neal, A
- Copyright date:
- 2014
- Notes:
- This thesis is not currently available in ORA.
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