Droplet interface bilayers for the study of membrane proteins

Thesis

Aqueous droplets submerged in an oil-lipid mixture become enclosed by a lipid monolayer. The droplets can be connected to form robust networks of droplet interface bilayers (DIBs) with functions such as a biobattery and a light sensor. The discovery and characterization of an engineered nanopore with diode-like properties is enabling the construction of DIB networks capable of biochemical computing. Moreover, DIB networks might be used as model systems for the study of membrane-based biolo...

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Authors: Hwang, W

• Publication date: 2008
• Type of award: MSc by Research
• Level of award: Masters
• Awarding institution: Oxford University, UK
• Language: English
• Keywords: asymmetric bilayers; droplet interface bilayer; ion channel; protein pore; protocell networks; molecular computing; double bilayers; electrical modeling
• Subjects: Biophysics; Chemical biology; Mathematical modeling (engineering); Chemistry & allied sciences; High-Throughput Screening; Electrical engineering; Nanomaterials; Biochemistry