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Intracellular chloride and hydrogen ion dynamics in the nervous system

Abstract:

Synaptic transmission in the nervous system involves the activation of receptor proteins that permit rapid transmembrane fluxes of ions. Ionic gradients across the membrane determine the direction and driving force for the flow of ions and are therefore crucial in setting the properties of synaptic transmission. These ionic gradients are established by a variety of mechanisms, including pump and transporter proteins. However, the gradients can be affected by periods of neural activity, whi...

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Institution:
University of Oxford
Research group:
Akerman lab
Oxford college:
Lincoln College
Department:
Medical Sciences Division - Pharmacology
Role:
Author

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Role:
Supervisor
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Funding agency for:
Joseph Valentino Raimondo
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:0b69b409-46e5-41ac-88c4-f1cfaf08ad24
Local pid:
ora:7643

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