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Thesis

Membrane transport alterations in disease states

Abstract:

The present thesis investigates cell membrane abnormalities in selected diseases. Membrane transport systems are studied in chronic renal failure (CRF), endstage diabetic nephropathy, renal transplantation and atherosclerotic vascular disease. The role of membrane cholesterol concentration in modulating transport activity is also explored.

Erythrocyte choline uptake is elevated in CRF and here it is shown that transporter activity returns to normal following a successful kidney tran...

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Peer review status:
Peer reviewed

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Department:
University of Oxford
Role:
Author
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:0b081bcd-4484-474c-bdb0-83e14da8265b
Local pid:
polonsky:5:22
Source identifiers:
603841288
Deposit date:
2017-10-05

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