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Thesis

Epicardial signalling in mammalian heart regeneration

Abstract:

Whilst lower vertebrate species, such as newt and zebrafish, can regenerate their hearts following substantial injury throughout life, humans and other adult mammals undergo cardiac scarring and remodelling in response to myocardial infarction (MI), which leads to chronic heart failure. However, recent work has identified a 'regenerative window' in mammals such that the 1 day-old mouse (P1) was able to regenerate lost myocardium following MI induced by ligation of the left anterior descen...

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Division:
MSD
Department:
Physiology Anatomy & Genetics
Department:
University of Oxford
Role:
Author

Contributors

Department:
University of Oxford
Role:
Supervisor
Marie Curie EU FP7 CardioNet award More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:09c20559-12c2-499b-87bd-43b5a1ce1258
Deposit date:
2016-04-27

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