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Thesis

Towards the synthesis of the ABC fragment of Pectenotoxin-4

Abstract:

This thesis details the optimisation and development to the synthesis of the ABC fragment of pectenotoxin-4, a 26-membered macrolide marine natural product bearing 19 stereogenic centres, three tetrahydrofuran rings, one spiroketal and one bicyclic ketal.

Introduction

This section briefly discusses the isolation, structure elucidation, and biological activity of penctenotoxins, along with a review of previous synthetic efforts on the pectenotoxin family, especially the...

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Division:
MPLS
Department:
History Faculty
Sub department:
Archaeology Research Lab
Department:
DARS
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:08df5365-d46a-4a82-b028-7c699b72fb4d
Deposit date:
2016-08-09

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