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Thesis

The acute effects of 5-MeO-DMT on behaviour, brain activity and arousal in mice

Abstract:

The serotonergic system plays an important role in the subcortical control of global sleep-wake states, as supported by observations that the administration of serotonergic psychedelics suppresses paradoxical sleep and results in increased sleep fragmentation. Growing evidence also suggests that a single psychedelic experience can positively impact long-term psychological well-being, with relevance to the treatment of psychiatric disorders often associated with disturbed sleep. Yet, little...

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy and Genetics
Oxford college:
Pembroke College
Role:
Author
ORCID:
0000-0002-1885-3963

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy and Genetics
Oxford college:
Hertford College
Role:
Supervisor
ORCID:
0000-0002-4336-6681
Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Oxford college:
St Edmund Hall
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Oxford college:
University College
Role:
Supervisor
ORCID:
0000-0001-7434-9713
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Examiner
ORCID:
0000-0003-3653-834X
Institution:
University of Bristol
Role:
Examiner


More from this funder
Funder identifier:
https://ror.org/00cwqg982
Grant:
BB/M011224/1


DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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