Thesis
The influence of invariant natural killer T cells on myeloid-derived suppressor cell generation and function
- Abstract:
-
The absence of invariant Natural Killer T cells (iNKT cells) in mice infected with Influenza A virus (flu) has previously been shown to augment the expansion of Myeloid-derived suppressor cells (MDSCs), a bone marrow derived population that powerfully suppress the development of viral and tumor immune responses. Moreover, iNKT cell adoptive transfer into flu-infected mice has been shown to abolish the expansion and flu-induced suppressive activity of the MDSCs in a CD1d- and CD40-dependent...
Expand abstract
Actions
Funding
Bibliographic Details
- Publication date:
- 2011
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:07ab563a-7455-4f69-bca0-3b409b72d2f7
- Local pid:
- ora:9280
- Deposit date:
- 2014-11-07
Terms of use
- Copyright holder:
- Arscott, R
- Copyright date:
- 2011
- Notes:
- This thesis is not currently available on ORA.
If you are the owner of this record, you can report an update to it here: Report update to this record