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Thesis

Organic Brønsted acid-catalysed enantioselective N-acyliminium cyclisation cascades

Abstract:

This thesis concerns the development of the first BINOL phosphoric acid (BPA) catalysed enantioselective N-acyliminium cyclisation reactions and their incorporation into domino sequences that allow for the construction of architecturally complex enantioenriched polycycles in a single step from easily accessible starting materials. More specifically, this thesis deals with the discovery of a BPA-catalysed enantioselective N-acyliminium cyclisation cascade of enol lactones and tryptamines. Its ...

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Chemistry Research Laboratory
Research group:
Darren J. Dixon Group
Oxford college:
Magdalen College
Role:
Author
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Division:
MPLS
Department:
Chemistry
Role:
Author

Contributors

Role:
Supervisor
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Name:
EPSRC/Pfizer
Funding agency for:
Muratore, M
Publication date:
2010
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:07a40a20-b71f-47f4-b549-bf9d7ca27043
Local pid:
ora:5170
Deposit date:
2011-03-24

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