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Thesis

A glycopore for bacterial sensing

Abstract:

Increasing antibiotic resistance has created a need to develop rapid and reliable methods to identify bacteria and provide pertinent information to ensure suitable antibiotics or sugar therapeutics can be chosen for treatment. Carbohydrate structures attached to proteins on host cell surfaces provide a binding point for many pathogens, including bacteria. These structures can be mimicked using single monosaccharides glycosylated to alpha-hemolysin (alpha-HL). Alpha-HL is a beta-barrel pore-fo...

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Subgroup:
Organic Chemistry
Research group:
Hagan Bayley Laboratory
Oxford college:
Oriel College
Role:
Author

Contributors

Division:
MPLS
Department:
Chemistry
Role:
Supervisor
Division:
MPLS
Department:
Chemistry
Role:
Supervisor
More from this funder
Grant:
Funding agency for:
Shanley, SJ
Publication date:
2009
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:06fe9bce-6bf2-4f61-b4d8-014cb9df3fc0
Local pid:
ora:3384

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