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Thesis

The organisation and dynamics of Escherichia coli outer membrane proteins

Abstract:

The outer membrane of E. coli is a component of the cell envelope with significant physiological importance. This multifunctional membrane allows the influx of nutrients and simultaneously excludes toxic compounds, such as antibiotics, which must cross this membrane to elicit their cytotoxic effect. The composition and general structure of this membrane are well known, an asymmetric lipid bilayer containing LPS in the outer leaflet, phospholipids in the inner leaflet, densely populated by...

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Division:
MSD
Department:
Biochemistry
Role:
Author

Contributors

Role:
Contributor
Role:
Contributor
Role:
Contributor
Role:
Supervisor
ORCID:
0000-0002-3273-0302
Role:
Supervisor
ORCID:
0000-0003-2640-9560
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Name:
Medical Research Council
Funder identifier:
http://dx.doi.org/10.13039/501100000265
Grant:
BRT00030
Programme:
Medical Sciences Graduate School Studentship
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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