Thesis
A CRISPR-Cas9 screen for hepatocyte receptors for malaria parasite invasion
- Abstract:
-
More than 2 billion people are at risk of contracting malaria, and around half a million die every year. Malaria is transmitted by sporozoites from Anopheles female mosquitoes to human host during a blood meal. From the host dermal layer, sporozoites travel to the liver, traverse through multiple hepatocytes until stopping in one last cell. They then establish a productive cell invasion, followed by a parasitophorous vacuole formation. Inside this vacuole, sporozoites develop into thousand...
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Authors
Contributors
+ Douglas, A
Role:
Supervisor
ORCID:
0000-0002-5410-7562
+ Spencer, A
Role:
Supervisor
ORCID:
0000-0001-7958-6961
Bibliographic Details
- Type of award:
- MSc by Research
- Level of award:
- Masters
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Deposit date:
- 2021-04-07
Related Items
Terms of use
- Copyright holder:
- Lee, Juliana Jung-Mee
- Copyright date:
- 2021
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