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Thesis

The role of innate lymphoid cells in intestinal inflammation

Abstract:

A breakdown of intestinal homeostasis due to dysregulated immune responses against intestinal bacteria underlies the pathogenesis of inflammatory bowel disease (IBD) in genetically susceptible individuals. Amongst mucosal immune cells, innate lymphoid cells (ILCs) are a heterogeneous group of cells whose functions in pathogenic inflammatory processes in the intestine are beginning to emerge from experimental murine models. However, less is known about the role of ILCs in chronic intestinal...

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Department:
Magdalen College, Oxford

Contributors

Department:
Nuffield Department of Medicine, University of Oxford
Role:
Supervisor
Department:
Kennedy Institute of Rheumatology, University of Oxford
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:

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