Thesis
Neuronal control of cardiac excitability in pro-hypertensive states
- Abstract:
-
Hypertension is associated with marked cardiac sympathetic over-activity and end organ hyper-responsiveness. The sympathetic dysfunction is caused by aberrant calcium (Ca2+) handling resulting in enhanced neurotransmission. However, it remains unclear whether the sympathetic neuron or the myocytes is the primary driver behind the initiation and maintenance of the autonomic phenotype. The work in this thesis characterises the Ca2+ dysfunction and regulation at the memb...
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Authors
Contributors
+ Paterson, D
Department:
University of Oxford
Role:
Supervisor
+ Paton, J
Department:
University of Bristol
Role:
Examiner
+ Lei, M
Department:
University of Oxford
Role:
Examiner
Funding
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:04d38eb6-ea66-4283-91ab-dd75bca246e9
- Deposit date:
- 2017-04-01
Related Items
Terms of use
- Copyright holder:
- Larsen, H; . Hege Ekeberg Larsen
- Copyright date:
- 2016
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