Thesis
A study of the reactions of flavanoids with nucleophiles
- Abstract:
-
The reactions with nucleophiles of 4-substituted flavans variously methoxylated are studied. The partial epimerisation of 4β-acetoxyflavans in acetic acid/acetic anhydride mixtures and of flavan-4β-ols in aqueous acid, providing preparatively useful routes to 4α-acetoxyflavans and flavan-4α-ols, occur by an SN1 mechanism. Reaction is greatly facilitated by methoxyl groups at the 5- and, especially, the 7-position. No effect of B-ring substitution on reaction rates was detected. ...
Expand abstract
- Peer review status:
- Peer reviewed
Actions
Authors
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- UUID:
-
uuid:039d7203-b2bb-4d37-9986-a738fb1857fe
- Local pid:
- polonsky:12:4
- Source identifiers:
-
601870725
- Deposit date:
- 2017-10-05
Terms of use
- Copyright holder:
- Attwood, M; Attwood, M R
- Copyright date:
- 1977
- Notes:
- This thesis was digitised thanks to the generosity of Dr Leonard Polonsky
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record