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Genetic studies in ulcerative colitis

Abstract:

Inflammatory bowel diseases (IBD), encompassing ulcerative colitis (UC) and Crohn’s disease (CD), are lifelong inflammatory disorders of complex and multifactorial aetiology. Genetic studies have played an important role in the identification of immunological pathways involved in the pathogenesis of IBD. Genome wide association studies have revealed more than 160 genetic polymorphisms associated with IBD, although the expected heritability in UC is smaller than for CD, and the relationship...

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Institution:
University of Oxford
Oxford college:
Linacre College
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - NDM John Radcliffe

Contributors

Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Publication date:
2015
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
Oxford University, UK
URN:
uuid:0381a359-b909-4d21-af68-9e427bfacc7f
Local pid:
ora:11538

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