Magnetically-activated DNA and RNA

Thesis

Nucleic acids serve as the fundamental building blocks for life, encoding genetic information that enable organisms to function. Ground-breaking research translating nucleic acids into therapeutic modalities has culminated into more than 21 approved drugs, including the mRNA-based vaccines for COVID-19. Their simplicity in design and ability to target disease-causing genes that are deemed “undruggable” using conventional small molecules has accelerated research efforts. However, their suscept...

Expand abstract

Authors: Parkes, E

• DOI: 10.5287/ora-qozjzmew6
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: proteins; synthetic cells; magnetic nanoparticles; magnetic hyperthermia; nucleic acids
• Subjects: Chemical biology; Chemistry