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Laurdan and Di-4-ANEPPDHQ probe different properties of the membrane

Abstract:

Lipid packing is a crucial feature of cellular membranes. Quantitative analysis of membrane lipid packing can be achieved using polarity sensitive probes whose emission spectrum depends on the lipid packing. However, detailed insights into the exact mechanisms that cause the changes in the spectra are necessary to interpret experimental fluorescence emission data correctly. Here, we analysed frequently used polarity sensitive probes, Laurdan and di-4-ANEPPDHQ, to test whether the underlying p...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1088/1361-6463/aa5dbc

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Department:
Oxford, MSD, RDM, RDM - Investigative Medicine Division
Role:
Author
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Department:
Oxford, MSD, RDM, RDM - Investigative Medicine Division
Role:
Author
More by this author
Department:
Oxford, MSD, RDM, RDM - Investigative Medicine Division
Role:
Author
Wolfson Foundation More from this funder
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Publisher:
IOP Publishing Publisher's website
Journal:
Journal of Physics D: Applied Physics Journal website
Volume:
50
Issue:
13
Pages:
134004
Publication date:
2017-03-07
Acceptance date:
2017-02-02
DOI:
EISSN:
1361-6463
ISSN:
0022-3727
Pubs id:
pubs:687132
URN:
uri:ff80e6ac-bfad-4a3d-9118-116b44429540
UUID:
uuid:ff80e6ac-bfad-4a3d-9118-116b44429540
Local pid:
pubs:687132
Keywords:

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