Journal article
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
- Abstract:
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INTRODUCTION
COVID-19 became a global pandemic partially as a result of the lack of easily deployable, broad-spectrum oral antivirals, which complicated its containment. Even endemically, and with effective vaccinations, it will continue to cause acute disease, death, and long-term sequelae globally unless there are accessible treatments. COVID-19 is not an isolated event but instead is the latest example of a viral pandemic threat to human health. Therefore, antiviral ... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
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(Preview, Accepted manuscript, pdf, 1.4MB, Terms of use)
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- Publisher copy:
- 10.1126/science.abo7201
Authors
- Publisher:
- American Association for the Advancement of Science
- Journal:
- Science More from this journal
- Volume:
- 382
- Issue:
- 6671
- Article number:
- eabo7201
- Place of publication:
- United States
- Publication date:
- 2023-11-10
- Acceptance date:
- 2023-10-09
- DOI:
- EISSN:
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1095-9203
- ISSN:
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0036-8075
- Pmid:
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37943932
- Language:
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English
- Keywords:
- Pubs id:
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1560633
- Local pid:
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pubs:1560633
- Deposit date:
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2024-01-16
- ARK identifier:
Terms of use
- Copyright holder:
- Boby et al
- Copyright date:
- 2023
- Rights statement:
- © 2023 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works https://www.sciencemag.org/about/science-licenses-journal-article-reuse This is an article distributed under the terms of the Science Journals Default License.
- Notes:
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This research was funded in part, by the Wellcome Trust [Grant number 209407/Z/17/Z]. For the purpose of open access, the author has applied a CC-BY public copyright license to any Author Accepted Manuscript version arising from this submission.
This is the accepted manuscript version of the article. The final version is available from American Association for the Advancement of Science at: 10.1126/science.abo7201
- Licence:
- CC Attribution (CC BY)
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