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A molecular clock dates the common ancestor of European-type porcine reproductive and respiratory syndrome virus at more than 10 years before the emergence of disease.

Abstract:

The disease caused by porcine reproductive and respiratory syndrome virus (PRRSV) emerged independently and almost simultaneously in Europe (1990) and North America (1987). The original reservoir of the virus and the date it entered the pig populations is not known. In this study, we demonstrate an accurate molecular clock for the European PRRSV ORF 3 gene, place the root in the genealogy, estimate the rate of nucleotide substitution, and date the most recent common viral ancestor of the data...

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Publication status:
Published

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Publisher copy:
10.1006/viro.2001.1102

Authors


Forsberg, R More by this author
Oleksiewicz, MB More by this author
Petersen, AM More by this author
Bøtner, A More by this author
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Journal:
Virology
Volume:
289
Issue:
2
Pages:
174-179
Publication date:
2001-10-05
DOI:
EISSN:
1096-0341
ISSN:
0042-6822
URN:
uuid:ff5c738a-3ac0-48d6-b96a-4567257dc32a
Source identifiers:
102842
Local pid:
pubs:102842

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