Reptile scale paradigm: Evo-Devo, pattern formation and regeneration.

Journal article

The purpose of this perspective is to highlight the merit of the reptile integument as an experimental model. Reptiles represent the first amniotes. From stem reptiles, extant reptiles, birds and mammals have evolved. Mammal hairs and feathers evolved from Therapsid and Sauropsid reptiles, respectively. The early reptilian integument had to adapt to the challenges of terrestrial life, developing a multi-layered stratum corneum capable of barrier function and ultraviolet protection. For better...

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Authors: Chang, C; Wu, P; Baker, R; Maini, P; Alibardi, L

• Publication status: Published
• Journal: International journal of developmental biology
• Volume: 53
• Issue: 5-6
• Pages: 813-826
• Publication date: 2009-01-01
• DOI: 10.1387/ijdb.072556cc
• EISSN: 1696-3547
• ISSN: 0214-6282
• Language: English
• Keywords: Homeostasis; Hair Follicle; Body Patterning; Mammals; Diffusion; Animals; Skin; Reptiles; Skin Physiological Phenomena; Birds; Regeneration; Biological Evolution; Models, Biological