- Abstract:
-
A major unresolved issue in developmental biology is the precise mechanism whereby the sperm activates the oocyte. With the discovery that calcium signals are the primary trigger for oocyte activation, a key remaining question became the identification of the signaling protein that mediates such calcium signals at fertilization. A major step forward came in 2002 with the discovery of a sperm-specific mammalian phospholipase C called phospholipase C zeta (PLCζ), which had the expected properti...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/mrd.21359
-
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- Journal:
- Molecular reproduction and development
- Volume:
- 78
- Issue:
- 10-11
- Pages:
- 846-853
- Publication date:
- 2011
- DOI:
- EISSN:
-
1098-2795
- ISSN:
-
1040-452X
- URN:
-
uuid:fedd7026-4677-466b-9937-7d5c5a19d0e4
- Source identifiers:
-
185383
- Local pid:
- pubs:185383
- Copyright date:
- 2011
Journal article
PLCζ and its role as a trigger of development in vertebrates.
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