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Population pharmacokinetic and pharmacodynamic properties of artesunate in patients with artemisinin sensitive and resistant infections in Southern Myanmar

Abstract:

Background: Artemisinins are the most effective anti-malarial drugs for uncomplicated and severe Plasmodium falciparum malaria. However, widespread artemisinin resistance in the Greater Mekong Region of Southeast Asia is threatining our ability to control and eliminate malaria. This work aimed to evaluate the pharmacokinetic and pharmacodynamic properties of artesunate and its active metabolite, dihydroartemisinin, in patients with sensitive and resistant falc...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
BioMed Central
Journal:
Malaria Journal More from this journal
Volume:
17
Article number:
126
Publication date:
2018-03-23
Acceptance date:
2018-03-14
EISSN:
1475-2875
Keywords:
Pubs id:
pubs:829607
UUID:
uuid:febb68c7-c04b-473a-a17e-585fc3219f78
Local pid:
pubs:829607
Source identifiers:
829607
Deposit date:
2018-03-15

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