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Journal article

The new immunosuppression: intervention at the dendritic cell-T-cell interface.

Abstract:

Dendritic cells (DCs) play an important role in initiating and directing T-cells towards immunity or tolerance. An important aim of emerging immunosuppressive strategies is to ensure that antigen is perceived in a 'tolerogenic context'. This would have obvious benefit in minimising the need for long-term drug maintenance in organ transplantation, hypersensitivity and autoimmune diseases. Here we review the biology of the interplay between the DC and T-cell, with a specific focus on therapeuti...

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Publisher copy:
10.2174/156800805774912935

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Current drug targets. Immune, endocrine and metabolic disorders More from this journal
Volume:
5
Issue:
4
Pages:
397-411
Publication date:
2005-12-01
DOI:
EISSN:
0000-0000
ISSN:
1568-0088
Language:
English
Keywords:
Pubs id:
pubs:15170
UUID:
uuid:feaa67c8-2ef3-4d4c-bf11-5a7c7918e92f
Local pid:
pubs:15170
Source identifiers:
15170
Deposit date:
2012-12-19

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