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Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial.

Abstract:

BACKGROUND: An increased rate of brain atrophy is often observed in older subjects, in particular those who suffer from cognitive decline. Homocysteine is a risk factor for brain atrophy, cognitive impairment and dementia. Plasma concentrations of homocysteine can be lowered by dietary administration of B vitamins. OBJECTIVE: To determine whether supplementation with B vitamins that lower levels of plasma total homocysteine can slow the rate of brain atrophy in subjects with mild cognitive im...

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Publication status:
Published

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Journal:
PloS one More from this journal
Volume:
5
Issue:
9
Pages:
e12244
Publication date:
2010-01-01
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Language:
English
Keywords:
Pubs id:
pubs:116949
UUID:
uuid:fe653787-7fbf-44f1-92ac-d6d14a8a7bd1
Local pid:
pubs:116949
Source identifiers:
116949
Deposit date:
2012-12-19

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