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Cutting edge: identification of E-cadherin as a ligand for the murine killer cell lectin-like receptor G1.

Abstract:

The killer cell lectin-like receptor G1 (KLRG1) is expressed by NK cells and by T cells. In both humans and mice, KLRG1 identifies Ag-experienced T cells that are impaired in their proliferative capacity but are capable of performing effector functions. In this study, we identified E-cadherin as a ligand for murine KLRG1 by using fluorescently labeled, soluble tetrameric complexes of the extracellular domain of the murine KLRG1 molecule as staining reagents in expression cloning. Ectopic expr...

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Publication status:
Published

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Publisher copy:
10.4049/jimmunol.176.3.1311

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Journal:
Journal of Immunology More from this journal
Volume:
176
Issue:
3
Pages:
1311-1315
Publication date:
2006-02-01
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
Language:
English
Keywords:
Pubs id:
pubs:469698
UUID:
uuid:fe23c35b-4b83-4c7e-b0c0-c867725990af
Local pid:
pubs:469698
Source identifiers:
469698
Deposit date:
2014-06-18

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