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Alternative molecular methods for improved detection of meningococcal carriage and measurement of bacterial density

Abstract:

Background: Conventional methods for detecting pharyngeal carriage of Neisseria meningitidis (Nm) are complex. There is a need for simpler methods with improved performance. We have investigated two alternative approaches.
Methods: Three pharyngeal swabs were collected from 999 pupils aged 10 to 18 years in The Gambia. Carriage of Nm was investigated using three different methods: (i) plating on Thayer-Martin selective medium and testing by conventional microbiological methods followed...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1128/JCM.01428-16

Authors


Manigart, O More by this author
Okeakpu, J More by this author
Odutola, A More by this author
More by this author
Department:
Hertford College
Bill and Melinda Gates Foundation More from this funder
Wellcome Trust More from this funder
Meningitis Research Foundation More from this funder
Publisher:
American Society for Microbiology Publisher's website
Journal:
Journal of Clinical Microbiology Journal website
Publication date:
2016-08-31
Acceptance date:
2016-08-15
DOI:
EISSN:
1098-660X
ISSN:
0095-1137
Pubs id:
pubs:638878
URN:
uri:fde678b2-68f0-4f60-839a-275088cfe327
UUID:
fde678b2-68f0-4f60-839a-275088cfe327
Local pid:
pubs:638878

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