Journal article
Viral load, clinical disease severity and cellular immune responses in primary varicella zoster virus infection in Sri Lanka.
- Abstract:
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BACKGROUND: In Sri Lanka, varicella zoster virus (VZV) is typically acquired during adulthood with significant associated disease morbidity and mortality. T cells are believed to be important in the control of VZV replication and in the prevention of reactivation. The relationship between viral load, disease severity and cellular immune responses in primary VZV infection has not been well studied. METHODOLOGY: We used IFNgamma ELISpot assays and MHC class II tetramers based on VZV gE and IE63...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 236.3KB)
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- Publisher copy:
- 10.1371/journal.pone.0003789
Authors
Funding
NIHR Biomedical Research Centre Programme
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Medical Research Council
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Commonwealth Commission
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 3
- Issue:
- 11
- Pages:
- e3789
- Publication date:
- 2008-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- Source identifiers:
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15821
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:15821
- UUID:
-
uuid:fde5a64c-457c-4b6e-9c48-2ad2e7829aa6
- Local pid:
- pubs:15821
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Malavige et al
- Copyright date:
- 2008
- Notes:
- Copyright 2008 Malavige et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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