- Abstract:
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BACKGROUND: In Sri Lanka, varicella zoster virus (VZV) is typically acquired during adulthood with significant associated disease morbidity and mortality. T cells are believed to be important in the control of VZV replication and in the prevention of reactivation. The relationship between viral load, disease severity and cellular immune responses in primary VZV infection has not been well studied. METHODOLOGY: We used IFNgamma ELISpot assays and MHC class II tetramers based on VZV gE and IE63...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
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(pdf, 236.3KB)
-
- Publisher copy:
- 10.1371/journal.pone.0003789
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 3
- Issue:
- 11
- Pages:
- e3789
- Publication date:
- 2008-01-05
- DOI:
- EISSN:
-
1932-6203
- ISSN:
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1932-6203
- URN:
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uuid:fde5a64c-457c-4b6e-9c48-2ad2e7829aa6
- Source identifiers:
-
15821
- Local pid:
- pubs:15821
- Copyright holder:
- Malavige et al.
- Copyright date:
- 2008
- Notes:
- Copyright 2008 Malavige et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
Viral load, clinical disease severity and cellular immune responses in primary varicella zoster virus infection in Sri Lanka.
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