BACKGROUND: In Sri Lanka, varicella zoster virus (VZV) is typically acquired during adulthood with significant associated disease morbidity and mortality. T cells are believed to be important in the control of VZV replication and in the prevention of reactivation. The relationship between viral load, disease severity and cellular immune responses in primary VZV infection has not been well studied. METHODOLOGY: We used IFNgamma ELISpot assays and MHC class II tetramers based on VZV gE and IE63...Expand abstract
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- Peer review status:
- Peer reviewed
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- Copyright holder:
- Malavige et al.
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- Copyright 2008 Malavige et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Viral load, clinical disease severity and cellular immune responses in primary varicella zoster virus infection in Sri Lanka.
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