Journal article icon

Journal article

Multiscale analysis of T cell activation: Correlating in vitro and in vivo analysis of the immunological synapse

Abstract:

Recently implemented fluorescence imaging techniques, such as total internal reflection fluorescence microscopy and two-photon laser scanning micro-scopy, have made possible multiscale analysis of the immune response from single molecules in an interface to cells moving in lymphoid tissues and tumors. In this review, we consider components of T cell sensitivity: the immunological synapse, the coordination of migration, and antigen recognition in vivo. Potency, dose, and detection threshold fo...

Expand abstract

Actions


Access Document


Publisher copy:
10.1007/978-3-540-93864-4-3

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Current Topics in Microbiology and Immunology
Volume:
334
Issue:
1
Pages:
47-70
Publication date:
2009
DOI:
ISSN:
0070-217X
URN:
uuid:fdd3e2ee-6f5f-465b-8fda-c713a3aac8e4
Source identifiers:
426328
Local pid:
pubs:426328
Language:
English

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP