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Journal article

Metabolic mechanisms in heart failure.

Abstract:

Although neurohumoral antagonism has successfully reduced heart failure morbidity and mortality, the residual disability and death rate remains unacceptably high. Though abnormalities of myocardial metabolism are associated with heart failure, recent data suggest that heart failure may itself promote metabolic changes such as insulin resistance, in part through neurohumoral activation. A detrimental self-perpetuating cycle (heart failure --> altered metabolism --> heart failure) that pr...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
Circulation More from this journal
Volume:
116
Issue:
4
Pages:
434-448
Publication date:
2007-07-01
DOI:
EISSN:
1524-4539
ISSN:
0009-7322
Language:
English
Keywords:
Pubs id:
pubs:164579
UUID:
uuid:fdd1ef8e-7236-449e-99ab-74dc91789543
Local pid:
pubs:164579
Source identifiers:
164579
Deposit date:
2012-12-19

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