Journal article
Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials
- Abstract:
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Background
Statin therapy is effective for the prevention of atherosclerotic cardiovascular disease and is widely prescribed, but there are persisting concerns that statin therapy might frequently cause muscle pain or weakness. We aimed to address these through an individual participant data meta-analysis of all recorded adverse muscle events in large, long-term, randomised, double-blind trials of statin therapy.
Methods
Randomised trials of st... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 1.0MB, Terms of use)
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- Publisher copy:
- 10.1016/s0140-6736(22)01545-8
Authors
- Publisher:
- Elsevier
- Journal:
- The Lancet More from this journal
- Volume:
- 400
- Issue:
- 10355
- Pages:
- 832-845
- Publication date:
- 2022-09-01
- Acceptance date:
- 2022-08-29
- DOI:
- EISSN:
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1474-547X
- ISSN:
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0140-6736
- Pmid:
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36049498
- Language:
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English
- Keywords:
- Pubs id:
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1279372
- Local pid:
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pubs:1279372
- Deposit date:
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2022-09-28
- ARK identifier:
Terms of use
- Copyright holder:
- Cholesterol Treatment Trialists' Collaboration
- Copyright date:
- 2022
- Rights statement:
- © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
- Licence:
- CC Attribution (CC BY)
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