- Abstract:
-
Genetic mouse models relevant to schizophrenia complement, and have to a large extent supplanted, pharmacological and lesion-based rat models. The main attraction is that they potentially have greater construct validity; however, they share the fundamental limitations of all animal models of psychiatric disorder, and must also be viewed in the context of the uncertain and complex genetic architecture of psychosis. Some of the key issues, including the choice of gene to target, the manner of i...
Expand abstract - Publication status:
- Published
- Journal:
- Neuropharmacology
- Volume:
- 62
- Issue:
- 3
- Pages:
- 1164-1167
- Publication date:
- 2012-03-05
- DOI:
- EISSN:
-
1873-7064
- ISSN:
-
0028-3908
- URN:
-
uuid:fd2c7fba-6065-4a7d-a839-290df0eaea84
- Source identifiers:
-
179564
- Local pid:
- pubs:179564
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
Genetic mouse models relevant to schizophrenia: taking stock and looking forward.
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