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Regioselective biotransformation of the dinitrile compounds 2-, 3- and 4-(cyanomethyl) benzonitrile by the soil bacterium Rhodococcus rhodochrous LL100-21.

Abstract:

The cyanomethyl benzonitrile compounds used for this study contain two cyano groups: a -CH(2)CN side chain, plus a cyano group attached to the benzene ring. The ortho, meta and para -CH(2)CN substituted compounds were biotransformed using whole cell suspensions of the bacterium Rhodococcus rhodochrous LL100-21. The bacterium had previously been grown on the mono-nitrile compounds propionitrile, benzonitrile or acetonitrile, inducing the formation of nitrile hydrolyzing enzymes.Suspensions of ...

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Publication status:
Published

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Authors


Claridge, TD More by this author
Pettman, AJ More by this author
Knowles, CJ More by this author
Journal:
Enzyme and microbial technology
Volume:
29
Issue:
1
Pages:
20-27
Publication date:
2001-07-05
DOI:
EISSN:
1879-0909
ISSN:
0141-0229
URN:
uuid:fd08f99c-4026-4572-a835-36a6a9485c98
Source identifiers:
117880
Local pid:
pubs:117880

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