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Tractography patterns of pedunculopontine nucleus deep brain stimulation

Abstract:

Deep brain stimulation of the pedunculopontine nucleus is a promising surgical procedure for the treatment of Parkinsonian gait and balance dysfunction. It has, however, produced mixed clinical results that are poorly understood. We used tractography with the aim to rationalise this heterogeneity. A cohort of eight patients with postural instability and gait disturbance (Parkinson’s disease subtype) underwent pre-operative structural and diffusion MRI, then progressed to deep brain stimulatio...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s00702-021-02327-x

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Role:
Author
ORCID:
0000-0002-3866-3833
Publisher:
Springer
Journal:
Journal of Neural Transmission More from this journal
Volume:
128
Issue:
5
Pages:
659-670
Publication date:
2021-03-29
Acceptance date:
2021-03-08
DOI:
EISSN:
1435-1463
ISSN:
0300-9564
Pmid:
33779812
Language:
English
Keywords:
Pubs id:
1169887
Local pid:
pubs:1169887
Deposit date:
2021-10-23

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