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Journal article

The diagnosis of pleural effusions

Abstract:
© 2015 Taylor and Francis. Pleural effusions arise from a variety of systemic, inflammatory, infectious and malignant conditions. Their precise etiological diagnosis depends on a combination of medical history, physical examination, imaging tests and pertinent pleural fluid analyses; including specific biomarkers (e.g., natriuretic peptides for heart failure, adenosine deaminase for tuberculosis, or mesothelin for mesothelioma). Invasive procedures, such as pleuroscopic biopsies, may be required for persistently symptomatic effusions which remain undiagnosed after the analysis of one or more pleural fluid samples. However, whenever parietal pleural nodularity or thickening exist, image-guided biopsies should first be attempted. This review addresses the current diagnostic approach to pleural effusions secondary to heart failure, pneumonia, cancer, tuberculosis and other less frequent conditions.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1586/17476348.2015.1098535

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author


Publisher:
Taylor and Francis
Journal:
Expert Review of Respiratory Medicine More from this journal
Volume:
9
Issue:
6
Pages:
801-815
Publication date:
2015-11-02
DOI:
EISSN:
1747-6356
ISSN:
1747-6348


Keywords:
Pubs id:
pubs:580797
UUID:
uuid:fc7db6e7-08fc-4f1f-8c48-fc0f1d0eb6af
Local pid:
pubs:580797
Source identifiers:
580797
Deposit date:
2016-06-03

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