Journal article icon

Journal article

Modelling spatially regulated B-catenin dynamics & invasion in intestinal crypts

Abstract:

Experimental data (e.g., genetic lineage and cell population studies) on intestinal crypts reveal that regulatory features of crypt behavior, such as control via morphogen gradients, are remarkably well conserved among numerous organisms (e.g., from mouse and rat to human) and throughout the different regions of the small and large intestines. In this article, we construct a partial differential equation model of a single colonic crypt that describes the spatial distribution of Wnt pathway pr...

Expand abstract

Actions


Access Document


Files:

Authors


Expand authors...
Publication date:
2010-01-01
URN:
uuid:fbcb5f60-a2f6-44ba-8d37-ed8590961da6
Local pid:
oai:eprints.maths.ox.ac.uk:946

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP