- Abstract:
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Purpose: We recently reported that the glycosaminoglycan hyaluronan (HA), which promotes inflammatory angiogenesis in other vascular beds, is an abundant component of the limbal extracellular matrix. Consequently, we have explored the possibility that HA contributes to lymphangiogenesis in the inflamed cornea.
Methods: To study the role of HA on lymphangiogenesis, we used mice lacking the hyaluronan synthases and injury models that induce lymphangi... Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
-
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(pdf, 1.7MB)
-
- Publisher copy:
- 10.1167/iovs.18-25920
-
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- Publisher:
- Association for Research in Vision and Ophthalmology Publisher's website
- Journal:
- Investigative Ophthalmology and Visual Science Journal website
- Volume:
- 60
- Issue:
- 4
- Publication date:
- 2019-03-01
- Acceptance date:
- 2019-02-12
- DOI:
- EISSN:
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1552-5783
- ISSN:
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0146-0404
- Pubs id:
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pubs:985758
- URN:
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uri:fbc4d845-19db-49b5-86bc-b4d5c40c0a1e
- UUID:
-
uuid:fbc4d845-19db-49b5-86bc-b4d5c40c0a1e
- Local pid:
- pubs:985758
- Language:
- English
- Keywords:
- Copyright holder:
- Sun et al.
- Copyright date:
- 2019
- Notes:
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Copyright 2019 The Authors. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Journal article
Hyaluronan derived from the limbus is a key regulator of corneal lymphangiogenesis
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