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Local differentiation in Plasmodium falciparum drug resistance genes in Sudan.

Abstract:

Studies of population genetic structure of parasites can be used to infer which parasite genes are under selection. Here, the population structure of 4 genes associated with drug resistance of Plasmodium falciparum (the chloroquine resistance transporter, pfcrt, dihydrofolate reductase, dhfr, dihydropteroate synthase, dhps, and multi-drug resistance, pfmdr-1) were examined in parasite populations in 3 villages in eastern Sudan and in an urban area of Khartoum, the capital. In order to differe...

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Publication status:
Published

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Publisher copy:
10.1017/s0031182003003020

Authors


Abdel-Muhsin, AA More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Awadalla, P More by this author
Suleiman, S More by this author
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Journal:
Parasitology
Volume:
126
Issue:
Pt 5
Pages:
391-400
Publication date:
2003-05-05
DOI:
EISSN:
1469-8161
ISSN:
0031-1820
URN:
uuid:fbbe3587-72ec-4728-8644-4afa591f16c0
Source identifiers:
90474
Local pid:
pubs:90474

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