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Journal article

Lineage-specific biology revealed by a finished genome assembly of the mouse

Abstract:

The mouse (Mus musculus) is the premier animal model for understanding human disease and development. Here we show that a comprehensive understanding of mouse biology is only possible with the availability of a finished, high-quality genome assembly. The finished clone-based assembly of the mouse strain C57BL/6J reported here has over 175,000 fewer gaps and over 139 Mb more of novel sequence, compared with the earlier MGSCv3 draft genome assembly. In a comprehensive analysis of this revised g...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1371/journal.pbio.1000112

Authors


Publisher:
Public Library of Science Publisher's website
Journal:
PLoS biology Journal website
Volume:
7
Issue:
5
Pages:
ARTN e1000112
Publication date:
2009-05-26
Acceptance date:
2009-04-03
DOI:
EISSN:
1545-7885
ISSN:
1544-9173
Source identifiers:
134377
Language:
English
Keywords:
UUID:
uuid:fbb2d290-18df-45b8-969c-9e84725eda81
Local pid:
pubs:134377
Deposit date:
2012-12-19

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