Journal article icon

Journal article

Intravenous quinidine for the treatment of severe falciparum malaria. Clinical and pharmacokinetic studies.

Abstract:

Quinidine has proved more effective than quinine against chloroquine-resistant Plasmodium falciparum both in vitro and in patients with uncomplicated disease. To examine the effectiveness and pharmacokinetics of quinidine for this use, we treated 14 patients who had severe falciparum malaria with intravenous quinidine gluconate; a loading dose of 15 mg of the base per kilogram of body weight was followed by 7.5 mg per kilogram every eight hours. Two of the five patients with cerebral malaria ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1056/nejm198505163122001

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Journal:
New England journal of medicine More from this journal
Volume:
312
Issue:
20
Pages:
1273-1278
Publication date:
1985-05-01
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Language:
English
Keywords:
Pubs id:
pubs:890
UUID:
uuid:fba1a49d-97d6-4bab-b4d2-05ffc73ca38e
Local pid:
pubs:890
Source identifiers:
890
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP