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A glycosynthase catalyst for the synthesis of flavonoid glycosides.

Abstract:
Mutant exposed! The synthetic utility of glycosynthase mutant enzymes has been expanded to allow the use of lipophilic acceptors, such as flavonoids, at rates comparable with those of natural glycosyltransferases. Sequential biocatalysis allows access to both di- and monosaccharide-modifled products as well as natural product glycoflavonoids. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH and Co. KGaA.
Publication status:
Published

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Publisher copy:
10.1002/anie.200604177

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
Angewandte Chemie (International ed. in English) More from this journal
Volume:
46
Issue:
21
Pages:
3885-3888
Publication date:
2007-01-01
DOI:
EISSN:
1521-3773
ISSN:
1433-7851


Language:
English
Keywords:
Pubs id:
pubs:33766
UUID:
uuid:fb95e48f-76f8-42cd-aa44-159a7a315b50
Local pid:
pubs:33766
Source identifiers:
33766
Deposit date:
2012-12-19

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