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Age-related changes in microvascular permeability: a significant factor in the susceptibility of children to shock?

Abstract:

During studies of the pathogenesis of dengue shock syndrome, a condition largely confined to childhood and characterized by a systemic increase in vascular permeability, we observed that healthy controls, age-matched to children with dengue shock syndrome, gave high values of filtration capacity (K(f)), a factor describing vascular permeability. We hypothesized that K(f) might be age dependent. Calf K(f) was studied in 89 healthy Vietnamese subjects aged 5 to 77 years. The K(f) was highest in...

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Publication status:
Published

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Publisher copy:
10.1042/cs19990296

Authors


Bethell, D More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
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Journal:
Clinical science (London, England : 1979)
Volume:
98
Issue:
2
Pages:
211-216
Publication date:
2000-02-05
DOI:
EISSN:
1470-8736
ISSN:
0143-5221
URN:
uuid:fb7d239e-7560-4c2c-97ea-e8545adfcc27
Source identifiers:
37356
Local pid:
pubs:37356

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