Journal article icon

Journal article

Pharmacokinetic predictors for recurrent malaria after dihydroartemisinin-piperaquine treatment of uncomplicated malaria in Ugandan infants.

Abstract:

BACKGROUND: Although dihydroartemisinin-piperaquine (DP) is used primarily in children, pharmacokinetic/pharmacodynamic (PK/PD) data on DP use in young children are lacking. METHODS: We conducted a prospective PK/PD study of piperaquine in 107 young children in Uganda. Samples were collected up to 28 days after 218 episodes of malaria treatment, which occurred during follow-up periods of up to 5 months. Malaria follow-up was conducted actively to day 28 and passively to day 63. RESULTS: The m...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/infdis/jit078

Authors


Journal:
Journal of infectious diseases More from this journal
Volume:
207
Issue:
11
Pages:
1646-1654
Publication date:
2013-06-01
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Language:
English
Keywords:
Pubs id:
pubs:387090
UUID:
uuid:fb764247-e1db-41c4-ae70-fb9abda808e4
Local pid:
pubs:387090
Source identifiers:
387090
Deposit date:
2013-11-17

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP