Journal article icon

Journal article

Generative AI and unstructured audio data for precision public health

Abstract:
In this study, transcribed videos about personal experiences with COVID-19 were used for variant classification. The o1 LLM was used to summarize the transcripts, excluding references to dates, vaccinations, testing methods, and other variables that were correlated with specific variants but unrelated to changes in the disease. This step was necessary to effectively simulate model deployment in the early days of a pandemic when subtle changes in symptomatology may be the only viable biomarkers of disease mutations. The embedded summaries were used for training a neural network to predict the variant status of the speaker as "Omicron" or "Pre-Omicron", resulting in an AUROC score of 0.823. This was compared to a neural network model trained on binary symptom data, which obtained a lower AUROC score of 0.769. Results of the study illustrated the future value of LLMs and audio data in the design of pandemic management tools for health systems.
Publication status:
Published
Peer review status:
Peer reviewed

Actions

Access Document

Files:
Publisher copy:
10.1038/s44401-025-00022-7

Authors

More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author


More from this funder
Funder identifier:
https://ror.org/01cwqze88
Grant:
ZIA CL040015
Programme:
Intramural
More from this funder
Funder identifier:
https://ror.org/029chgv08
Grant:
204904/Z/16/Z
More from this funder
Funder identifier:
https://ror.org/0439y7842
Grant:
EP/W031744/1


Publisher:
Springer Nature
Journal:
npj Health Systems More from this journal
Volume:
2
Issue:
1
Article number:
19
Place of publication:
England
Publication date:
2025-06-02
Acceptance date:
2025-04-21
DOI:
EISSN:
3005-1959
Pmid:
40470007


Language:
English
Pubs id:
2129590
Local pid:
pubs:2129590
Deposit date:
2025-07-03
ARK identifier:

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP