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Journal article

Imaging and modeling collagen architecture from the nano to micro scale.

Abstract:

The collagen meshwork plays a central role in the functioning of a range of tissues including cartilage, tendon, arteries, skin, bone and ligament. Because of its importance in function, it is of considerable interest for studying development, disease and regeneration processes. Here, we have used second harmonic generation (SHG) to image human tissues on the hundreds of micron scale, and developed a numerical model to quantitatively interpret the images in terms of the underlying collagen st...

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Publisher copy:
10.1364/BOE.5.000233

Authors


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Journal:
Biomed Opt Express
Volume:
5
Issue:
1
Pages:
233-243
Publication date:
2013-12-16
DOI:
EISSN:
2156-7085
ISSN:
2156-7085
URN:
uuid:fb19f1f7-857f-428a-abfd-72544f73b72c
Source identifiers:
445511
Local pid:
pubs:445511

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