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Journal article

ATRX and the replication of structured DNA.

Abstract:

Understanding the underlying molecular basis for disease can often be a prolonged and tortuous process with many false leads and blind alleys. Relating the cause of ATR-X syndrome to the function of the protein ATRX is a case in point. In this review we attempt to bring together the diverse biological phenomena associated with ATRX dysfunction with what has recently been discovered concerning the chromatin remodelling activity of this protein. This potentially casts light on how defective DNA...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.gde.2013.01.005

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Strategic
Role:
Author
Medical Research Council More from this funder
University of Oxford More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Current opinion in genetics and development Journal website
Volume:
23
Issue:
3
Pages:
289-294
Publication date:
2013-06-01
DOI:
EISSN:
1879-0380
ISSN:
0959-437X
Source identifiers:
387871
Language:
English
Keywords:
Pubs id:
pubs:387871
UUID:
uuid:fb020e95-e0a7-4949-81ff-e39ff98f2010
Local pid:
pubs:387871
Deposit date:
2013-11-16

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